compound 10 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T35398	MINA53 inhibitor (Compound 10)		Others
	MINA53 inhibitor (Compound 10) is an inhibitor of MINA53.		Others
T9658	DCZ3301	NPS ALX Compound 4a hydrochloride(1:1)(299433-10-6 Free base)	Others
	DCZ3301 is a novel aryl-guanidino inhibitor.		Others
T68594	NFAT:AP-1 inhibitor-10
	NFAT:AP-1 inhibitor-10 is a novel inhibitor of the NFAT:AP-1:DNA interaction on the ARRE-2 element, binding to DNA in a sequence-selective manner and inhibiting the transcription of the Il2 gene and several other cyclosp...
T17039	Terbogrel	BIBV 308SE	Prostaglandin Receptor
	Terbogrel is an oral thromboxane A2 receptor antagonist (IC50 is about 10 nM) and thromboxane A2 synthase inhibitor (IC50 is about 10 nM). Terbogrel is an antiplatelet compound that inhibits platelet aggregation and is a...		Prostaglandin Receptor
T9856	FLT3-IN-10	2-Oxazolamine, 5-(4-fluorophenyl)-N-phenyl-	FLT
	FLT3-IN-10 (2-Oxazolamine, 5-(4-fluorophenyl)-N-phenyl-) (compound 7c) is a potent inhibitor of FMS-like tyrosine kinase 3 (FLT3). FLT3-IN-10 shows the potential for the treatment of FLT3-mutated acute myeloid leukemia (...		FLT
T19480	NO-prednisolone	NCX-1015	IL Receptor
	NO-prednisolone (NCX-1015) is a compound that effectively stimulates the production of IL-10 in vivo. It is a Prednisolone derivative that releases nitric oxide (NO).		IL Receptor
T2712	Nifekalant hydrochloride		Potassium Channel
	Nifekalant hydrochloride is an IKr potassium channel blocker with an IC50 of 10 µM. It is a Class III antiarrhythmic compound and can be used in the study of tachyarrhythmias.		Potassium Channel
T11138L	LHF-535		Virus Protease , Antiviral
	LHF-535 is an antiviral compound. It has EC50s of <1 μM, <1 μM, <1 μM, and 1-10 μM for Lassa, Machupo, Junin, and VSVg virus, respectively.		Virus Protease , Antiviral
T72025	PCSK9-IN-10		Serine/threonin kinase
	PCSK9-IN-10, a potent and orally active inhibitor of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9), exhibits a half-maximal inhibitory concentration (IC50) of 6.4 µM. By enhancing the expression of Low-Density Li...		Serine/threonin kinase
T61969	AChE/BChE-IN-10		AChR , AChE
	AChE/BChE-IN-10 is a potent dual inhibitor of AChE and BChE with IC50 values of 0.176, and 0.47 μM, respectively. AChE/BChE-IN-10 exhibits good blood brain barrier permeability. AChE/BChE-IN-10 can inhibit Aβ-aggregation...		AChR , AChE
T1521	(±)-10-Hydroxycamptothecin	Hydroxy Camptothecine,10-Hydroxycamptothecin	Topoisomerase
	(±)-10-Hydroxycamptothecin (Hydroxy Camptothecine) is an alkaloid isolated from the stem wood of the Chinese tree, Camptotheca acuminata. This compound selectively inhibits the nuclear enzyme DNA topoisomerase, type I. S...		Topoisomerase
T37341	N-Acetyltyramine		Antibacterial
	N-acetyltyramine is a metabolite of the biogenic amine tyramine . It enhances cytotoxicity of doxorubicin in resistant P388 murine leukemia cells with an IC50 value of 0.13 μg/ml compared with an IC50 value of 0.48 μg/ml...		Antibacterial
TQ0271	Falnidamol	BIBX 1382	EGFR
	Falnidamol (BIBX 1382) is an orally active, selective EGFR tyrosine kinase inhibitor with an IC50 of 3 nM. Falnidamol displays > 1000-fold lower potency against ErbB2 (IC50=3.4 μM) and a range of other related tyrosine k...		EGFR
T3812	(20R)-Ginsenoside Rg3	20(R)-Ginsenoside Rg3,(20R)Ginsenoside Rg3,20(R)-Propanaxadiol	Others
	(20R)-Ginsenoside Rg3 (20(R)-Propanaxadiol) is a compound with anti-aging and antifatigue activities.		Others
T1813	VGX-1027	VGX1027,VGX 1027,GIT 27	IL Receptor , TNF , Interleukin
	VGX-1027 (GIT 27) is an isoxazole compound with various immunomodulatory properties.		IL Receptor , TNF , Interleukin
T0486L	Irinotecan Hydrochloride	Camptothecin 11 hydrochloride,CPT-11 hydrochloride	Topoisomerase , Autophagy
	Irinotecan Hydrochloride (CPT-11 hydrochloride) is the hydrochloride salt of a semisynthetic derivative of camptothecin. Irinotecan, a prodrug, is converted to a biologically active metabolite 7-ethyl-10-hydroxy-camptoth...		Topoisomerase , Autophagy
T4752	1-Aminocyclopropane-1-carboxylic acid	1-Aminocyclopropanecarboxylic acid,1-Amino-1-carboxycyclopropane,ACC	Endogenous Metabolite , NMDAR
	1-Aminocyclopropane-1-carboxylic acid (ACC) is an intermediate in the synthesis of ethylene, the plant hormone responsible for biological processes ranging from seed germination to organ senescence. It is a small molecul...		Endogenous Metabolite , NMDAR
T2163	Dihydrocapsaicin	CCRIS1589,6,7-Dihydrocapsaicin,8-Methyl-N-vanillylnonanamide	Others , TRP/TRPV Channel
	Dihydrocapsaicin (CCRIS1589) is isolated from Capsicum fruit. Capsaicin is the primary active component of the heat and pain-eliciting lipid soluble fraction of the Capsicum pepper. Like capsaicin, dihydrocapsaicin is an...		Others , TRP/TRPV Channel
T36968	ARN-21934		Topoisomerase
	ARN-21934 is a potent, highly selective, blood-brain barrier (BBB) penetrant inhibitor for human topoisomerase II α over β. ARN-21934 inhibits DNA relaxation with an IC50 of 2 μM as compared to the anticancer agent Etopo...		Topoisomerase
T62210	Antileishmanial agent-10
	Antileishmanial agent-10 (Compound 7h) is an antiprotozoal agent.